Is Tramadol a blood thinner?

Tramadol is used to relieve moderate to moderately severe pain. Tramadol extended-release tablets are only used by people who are expected to need medication to relieve pain around-the-clock for a long time. Tramadol is in a class of medications called opiate agonists. It works by changing the way the body senses pain.

How should this medicine be used?

Tramadol comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet is usually taken with or without food every 4-6 hours as needed.

The extended-release tablet should be taken once a day. Take the extended-release tablet at about the same time of day every day, and either always take it with food or always take it without food. Take tramadol exactly as directed. Do not take more medication as a single dose or take more doses per day than prescribed by your doctor. Taking more tramadol than prescribed by your doctor may cause serious side effects or death. Your doctor may start you on a low dose of tramadol and gradually increase the amount of medication you take, not more often than every 3 days if you are taking the regular tablets or every 5 days if you are taking the extended-release tablets. Swallow the extended-release tablets whole; do not split, chew, or crush them. Do not snort (inhale powder from crushed tablet) or inject the dissolved extended-release tablets. Taking this medication in a way that is not recommended may cause serious side effects or death.

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Patients Prescribed Tramadol Less Likely To Develop Dependency

Author: Michael Connelly

Most people live their lives taking their health for granted, as long as they are feeling no pain. But if they happen to suffer a physical injury, the first thing on their mind is finding a way to reduce the pain. Tramadol is one of the most widely used pain relief medicines available to patients who are in need of treatment for moderate to severe pain. It is an analgesic, or pain killer that works on the brain and nervous systems in somewhat mysterious ways. While it is classified as an opioid, it is very much unlike any other pain relief medicine in this classification such as morhine and codeine. It is not considered to be a controlled substance in the United States, which means that it can be obtained with a standard prescription from any medical doctor. Patients can even buy Tramadol at an online pharmacy via one of the many US licensed pharmacies on the Internet.

A German pharmaceutical company named Grunenthal GmbH invented Tramadol in their laboratory near the end of the 1970s. At that time they gave it the name Tramal. Since then they have sold the rights to a wide variety of companies around the world who have come up with a lot of different names. A company in Argentina markets it as Calmador. In Sweden a company sells it as Tradolan. In Isreal it is sold as Tramadex, and in South Korea this particular medicine can be purchased as Tandol. Ultram and Ultracet are other names for this prescription drug in the United States. Today there are over 55 different brand names for Tramadol worldwide.

There is releatively little negative health related press attached to Tramadol as a prescription medicine, mostly because it is not abused recreationally as much as some other opioids. The reported negative side effects of Tramadoll abuse are nausea, abnormal sweating, vomiting, constipation and seizures. These side effects can create a very unpleasant experience if this drug is abused, which puts it low on the lists of prescription drugs for experimental drug users.

Tramadol is available by a prescription from US licensed physicians and legal to be purchased online at US licensed pharmacies or at any pharmacy. This is due to the fact that this synthetic agent is less likely to cause a dependency if used for an extended period of time. This is an important factor when doctors consider the long term health of their patients who take a prescribed medicine for pain.

Unlike other prescription drugs in its class, Tramadol has a relatively mild effect on the mu opioid receptor. This is a nerve receptor that is located in the periaqueductal grey area of the brain, otherwise known as the midbrain grey matter area. It is responsible for what is called the Gate Control Theory of pain relief. Opioids such as morphine and vicodin bind very easily to it and inhibit the pathway of the neurons that are being sent to the brain to register pain. The Gate Control Theory is the basis of most modern analgesics and it has revolutionized the way pain can be managed.

This affinity to the mu opioid receptor can also be responsible for the creation of a dependency to the opioid drug that is being used. However, Tramadol has a weaker affinity to this receptor than the other opioids in its class, which means that addiction is less likely to occur. Thus, the health of the patient is compromised less by taking this particular medicine to reduce their pain.

Tramadol can be taken in many different forms including orally in a pill or tablet form, rectally with suppositories, injected and with an IV in hospitals. The dosages range from 50 to 400 milligrams per day, which is determined by the attending physician.

While it is true that the mild agonism of the mu opioid receptor is partially responsible for the effectiveness of Tramadol in treating pain, doctors and scientists are not quite sure about the other details of why Tramadol works. They know that it is something to do with the effect it has on the noradrenergic and serotonergic systems in the human body.

The serotonergic system involves the neurotransmitter known as serotonin which is responsible for many different functions in the human body. Among its many duties serotonin is in charge of the regulation of various moods such as anger, as well as the regulation of sleeping patterns and appetite. It is created in the intestines by the amino acid tryptophan.

The noradrenergic system is responsible for such things as the fight or flight response we get when we are placed in a very stressful and dangerous situation. When a situation like this happens, norepinephrine which is also know as noradrenaline is sent to the part of the brain that controls attention and response processing. This hormone and neurotransmitter comes from a gland located in a part of the brain stem called the locus ceruleous. A neurotransmitter system is activated that sends neurons instantly along the spinal cord and distributes them to all parts of the body through millions of nerve pathways.

When norepinephrine is triggered the subjects heart rate increases, glucose is released into the bloodstream from stored up energy and all the muscles of the skeletin experience an increase in blood flow. The subject also experiences increased alertness and arousal. Studies have shown that the effect Tramadol has on the noradrenergic system may also have something to do with the decreased risk of developing a dependency, although the reason why is still not known.

Treating and controlling pain has come a long way in the past 100 years. The discovery of opioid based prescription drugs like morhine, codeine and vicodin have revolutionized pain treatment and brought relief to millions around the world who suffer from moderate to severe pain. However, there has been a negative health side effect from this benefit and it is the creation of dependencies on these drugs for millions of patients who took their prescribed pain medicine for extended periods of time.

Tramadol is a synthetic opioid medicine and it may be in the same class as the natural opiate based prescription drugs morphine and vicodin, but it has two very big differences from these two medicines. For one, it is not considered to be a controlled substance in the United States. This means that US licensed physicians can prescribe this analgesic to patients who can buy it at any pharmacy or online pharmacy that happens to be one of the many US licensed pharmacies on the Internet.

But the biggest thing that makes Tramadol different than other prescription drug opioids is that it can alleviate pain with a much lower chance of causing an addiction to the drug. This is very important when you consider the long term health of people who take pain medicine for extended periods of time.

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Chronic Pain

Chronic pain is defined as pain that lasts longer than 3 months. Chronic pain is different than acute pain in that it is not easy to find the cause.

By The EFIC (European Federation of IASP Chapters) statistics 50% of older peoples living in community and more then 80% living at home suffer from chronic pain. It is estimated that every second older citizen (over 65 years) in Europe.

Typical Chronic Pain Conditions

· Osteoarthritis
· Rheumatoid arthritis
· Low back, shoulder and neck pain
· Headache, including migraine
· Cancer pain
· Myofascial pain syndromes
· Post-thoracotomy pain
· Chronic regional pain syndromes
· Stump and phantom limb pain · Neuropathic pain
· Herpes zoster (shingles) and post-herpetic neuralgia
· Trigeminal neuralgia
· Diabetic neuropathy
· Temporomandibular Joint Disorder (TMJ)
· Postmastectomy pain
· Angina pectoris
· Chronic visceral pain syndromes

Treatment

Treatment for chronic pain depends on the cause and on the individual needs of the patient. Complete pain relief is not always possible; it is important for patients and physicians to work together to find the best treatment plan.

- Medications
- Aacupuncture
- Local electrical stimulation
- Brain stimulation

As you consider treatment options for your chronic pain, it's important that you learn as much as possible about your condition and how the treatments can affect it.

For Your Chronic Pain, Tramadol Can Provide Relief

One of the things that you should know about your chronic pain is that it is often very hard for you to find relief. There are so many things that you are going to have to learn to deal with while you are dealing with chronic pain, and sometimes life just simply can't stop because you don't feel well. Chronic pan can be something that has the potential to ruin your whole life, so for your chronic pain, Tramadol can cause you a lot of relief.

What Is It

When it comes to chronic pain, Tramadol is going to be a very strong pain killer that you can take on a regular basis to help you manage your pain. The thing about chronic pain, Tramadol , and other pain killers is that many times people who are dealing with chronic pain end up with drug addictions because they find themselves taking way more medication than they are supposed to. Tramadol can help you with your Chronic Pain more than you would ever be able to imagine.

This means that your pain might cause you even more pain. However, with chronic pain, Tramadol has a very low dosage, which means that it is going to be safe for you to take every day, and you wont' have to worry about getting into a situation where you might become addicted. That means for your chronic pain, Tramadol is going to be one of the best things that you can do for yourself. Talk to your doctor about your chronic pain, Tramadol , and other solutions.

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Neck Pain: Tips on Pain Relief and Prevention

Definition:

Neck pain is the sensation of discomfort in the neck area. Neck pain can result from disorders of any of the structures in the neck, including the cervical vertebrae.

What causes neck pain?

Many things can trigger neck pain. These include:

- Trauma or injury (damage to the muscles, tendons, and/or ligaments)
- Herniated cervical disk
- Worry and stress
- Tumors
- Falling and sleep in an awkward position
- Prolonged use of a computer keyboard

You feel as though your head is much heavier than it ever has been before

What can you do yourself?

- Stay as active as possible. Try to go to work and keep up your normal everyday activities - bed rest is not necessary. If you are given a neck-collar, try not to use this for more than one or two days.

- Remember that neck pain is rarely caused by a serious illness and will often disappear within a week.

- If you have had pains in the neck for a longer period, it is a good idea to consult your doctor or a physical therapist such as a chiropractor or physiotherapist.

- Sit in a neutral position looking straight ahead.

- Slowly tilt your head one inch to the right, and to the left

- Stretch your neck downward, moving your chin toward your chest. Hold for 10 seconds.

- In order to go about neck pain relief you should apply heat,ice to the sore area for 10-15 minutes every few hours. This will decrease inflammation and cramping.

- Massage the area gently.

- Take anti-inflammatory medications.

Tips for preventing neck pain :

- Take frequent breaks for a few seconds every hour from what you are doing to change position. Stretch and move stiff areas of your neck and shoulders.

- Keep heavy loads and things you lift close to you while lifting them.

- Lift with your legs instead of your back.

- Avoid reaching overhead with your arms and too far from your body.

- Avoid moving your neck up or down a lot.

Are you sitting comfortably?

1. Eyes should be level with the top of your computer screen or document holder, so that you are looking down slightly. Always look at your desk square-on.
2. Arms should be relaxed, with no tension in the wrists. The secret here is to chill. Don’t grip that mouse too tightly, and don’t stretch to reach it.
3. Sitting at your desk, your spine should be in a slight S-shaped curve. Adjust your chair so that the backrest fits into the lower, or small, of the back.
4. Avoid crossing your legs. Your knees should be in line with your pelvis, or slightly lower, and your lower legs at a right angle to your thighs.
5. Feet should be flat on the floor, or on a footrest.
6. Make sure that there is enough room under your desk to move your legs freely.
7. Your computer screen should be at arm’s length away; don’t stretch to reach your keyboard.

Author: Kate Whigton

Common symptoms include :



Symptoms are how the cause of your pain affects you.

Pain in your neck
Headaches
Pain in your shoulder, arm, or hand
Reduced range of motion in your neck
Numbness, weakness, and slower reflexes in your arms, hands,legs, or feet
Problems walking including a "spastic gait"
Muscle weakness in your legs
source: www.tramadolhome.com

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'My daughter died because they didn't care'

By Jessica Johnston Townsville Bulletin
October 11, 2008 07:18am

• Father lashes out at friends who 'let his girl die'
• Girl suffered drug overdose but no one called for help
• Local coverage at The Townsville Bulletin

A FATHER has lashed out at the"callous indifference" of youths who wouldn't call for help as his daughter slowly died of a drug overdose.

The anguish and anger at losing his youngest daughter Melanie from a drug overdose at a party was evident as Laurie Boyd made a heart-wrenching statement to a Townsville coroner yesterday.

Mr Boyd was emotional yet resolute as he described his family's eternal grief and his personal pain identifying the 16-year-old in the morgue, The Townsvile Bulletin reports.

Melanie Boyd begged her friends to call for help after taking a lethal cocktail of booze and drugs, the inquest was told.

But by the time an ambulance was called, three hours after she was found "blue" and "struggling to breathe", the popular Townsville private schoolgirl was dead.

"No father should be called upon to identify his daughter's body," he said.

"Mel's throat was swollen, it was grossly distorted from her efforts trying to breathe.

"No witness can tell me she was merely snoring, or breathing like she had the flu.

"She must have been struggling for breath for hours ... I hope that she was unconscious.

"She died alone in a strange house, I just hope she didn't die afraid.

"We loved her and miss her every day.

"We were so lucky this wasn't the first of three inquests ... that three other fathers didn't have to go to the ghastly place in the bowels of the hospital to identify their daughter.

"Why it was Mel, I'll never know."

A toxicology report showed Melanie had traces of the painkiller Tramadol, sedative Promazine and codeine in her system when she died.

There was no trace of amphetamine or any illicit drug.

Professor David Williams, who undertook the autopsy, indicated Melanie had ultimately drowned in her vomit, which caused her death.

"She would have gradually lost consciousness," Prof Williams said.

"I'm sure it would have been peaceful, yes."

Mr Boyd said the only two youths who seemed to comprehend the impact of Melanie's death were those who had also taken the lethal drug cocktail.

He said only one of the girls had "the courage and integrity'"to attend Mel's funeral, and to extend her sorrow and regret.

Mr Boyd lashed out at the "callous indifference, shallow vanity and mindless hedonism" shown by the four youths who hadn't called an ambulance for the sick girls.

He said the other schoolgirl, who can't be named because of her age and Matthew Aubrey, Kelly Neville and Zohe Horne had displayed little insight or sorrow.

"There is no doubt that Mel died because they did not care," he said.

"I have sat and listened to the evidence of a succession of young people who were present during the circumstances leading up to my daughter's death.

"At times I have found it difficult to control my rage and I think it fair to observe that many of us ... are bewildered by what we have heard.

"These people sat and watched Mel die for three hours and they will never be held responsible.

"These people will effectively get away with watching my daughter die."

Mr Boyd said he had been "bitterly angry" that the host and her family had appeared to run away to New Zealand to avoid the consequences' and made no attempt to contact him.

But he yesterday extended a message of forgiveness to the other parents, acknowledging they were doing what they thought was best for their child.

"I hope (the host) that you have all the opportunities that were denied to Melanie and I wish you well for the future," he said.

Read more at the Townsville Bulletin.

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Macon mother charged in 13-month-old's death

Source: www.macon.com

By Amy Leigh Womack - awomack@macon.com

The mother of a 13-month-old child found dead Aug. 18 has been charged with murder and cruelty to children in the second degree, according to Macon police.

Autumn Cameron was found dead by her mother, 27-year-old Lauren Cameron, at their family's apartment in the Overlook Gardens complex off Gray Highway, according to police.

Results of toxicology tests revealed the child's death was caused by tramadol, a narcotic-like pain reliever, according to a police report released Friday.

Cameron reportedly gave statements to the police that she was the owner of the medicine and that she was the child's caregiver at the time when she consumed the drug, according to the report.

Cameron is reported to have awakened about 10 a.m. Aug. 18 to find her daughter, dead, according to the police. When officers arrived, the child was lying on a sofa on her back.

Initial autopsy results were inconclusive as to how the child died.

Cameron was arrested Oct. 3 and is being held at the Bibb County jail without bond, according to jail records.

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US Drugstore | Tramadol Review

Author: us drugstore

Tramadol is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. It is a synthetic agent, and appears to have actions on the ?-opioid receptor as well as the noradrenergic and serotonergic systems. Tramadol was developed by the German pharmaceutical company Grünenthal GmbH in the late 1970s and marketed under the trade name Tramal. Grünenthal has also cross licensed the drug to many other pharmaceutical companies that market it under various names.

Specifically, tramadol comes in capsules, tablets, extended-release tablets, low-residue and/or uncoated tablets which can be taken by the sublingual and buccal routes, suppositories, effervescent tablets and powders, ampoules of sterile solution for SC, IM, and IV injection, powders for compounding, liquid for oral and sublingual administration -- in regular phials and bottles, dropper bottles, bottles with a pump similar to those used with liquid soap and phials with droppers built into the cap - as well as tablets and capsules containing paracetamol and aspirin.

Tramadol has a characteristic taste which is mildly bitter but much less so than morphine and codeine. Oral and sublingual drops and liquid preparations come with and without added flavouring. Its relative effectivness via transmucousal routes (sublingual, buccal, rectal) is around that of codeine and like codeine it is also metabolised in the liver to stronger metabolites (see below).

Doses range from 50-400 mg daily, maximum dose of 400 mg a day (webmed), with up to 600 mg daily when given IV/IM. The formulation containing APAP contains 37.5 mg of tramadol and 325 mg of paracetamol, intended for oral administration with a common dosing recommendation of one or two tabs every four to six hours.

Tramadol can be boosted in its analgesic effect with carisoprodol and meprobamate, benzodiazepines, and most antihistamines, especially promethazine, hydroxyzine, and orphenadrine.

Unlike most other opioids, Tramadol is not considered a controlled substance in many countries (the US and Australia, among others), and is available with a normal prescription. Tramadol is available over the counter without prescription in a few countries.[4] Sweden has as of May 2008 chosen to classify Tramadol as a controlled substance in the same way as codeine and dextropropoxyphene. This means that the substance is a scheduled drug. But unlike codeine and dextropropoxyphene, a normal prescription can be used at this time.[2] Tramadol is sometimes mistakenly classified as a non-opioid analgesic, because its abuse liability is lower than that of other opioids and because it has multiple mechanisms of action (including, but not limited to mu-opioid activity).

Tramadol is usually marketed as the hydrochloride salt (tramadol hydrochloride) and is available in both injectable (intravenous and/or intramuscular) and oral preparations. It is also available in conjunction with paracetamol (acetaminophen).

Source: www.articlesbase.com

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Tramadol Takes on Arthritis

By: John Scott

Arthritis, at its core is simply an inflammation of the joints. However, there are a lot of diseases associated with arthritis; such as osteoarthritis and rheumatoid arthritis. They range from mildly painful to intensely painful. For some of the mild cases simply taking a few aspirin gives enough comfort. But more intense cases require stronger medication. That's where Tramadol stands out in the crowd.

Everyone has, at some time in their life, had a doctor ask them to rate their pain on a scale of 1 to 10. Pain is such an individual experience that it's difficult for an outsider, who is not experiencing it, to really understand how bad it is. Not only does it vary in intensity, it can have a wide range of sensations as well. One person might have sharp pains while another could be having a dull ache. Worse, are the cases of the intense, persistent, throbbing pain. That's the kind of pain that Tramadol attacks.

It's important for sufferers to be able to accurately describe their pain. The more accurate they can be, the better. There is often more than one doctor involved in a patient's care. A family practitioner may refer the patient to a specialists. The specialist may ask a collegue's opinion. There are any number of reasons to be sure your description of the pain you're feeling is accurate.

The treatment of arthritis is not as simple as taking one form of treatment and following that one form. Several factors play into arthritis and several factors need to be addressed when treating it.

Diet is one of those factors. Weight loss can have a healing effect on arthritic conditions. It reduces stress on the joints and takes some of that wearing pressure off. However, diet can have more of an impact if the arthritis sufferer goes beyond just trying to lose weight. Eating a lot of marine oils from cold-water fish have proven to reduce inflammation in many joint conditions. Diets high in fish such as salmon, mackerel, and tuna can have a big impact on arthritis.

Exercise is another important factor in treating arthritis. Unlike joint injuries which need to be immobilized, joint diseases get a lot of benefit from keeping mobile, active, and limber. There are numerous activities that are great for people suffering from arthritis. Among them are stretching, walking, and swimming. In addition, physical therapists will introduce patients to a variety of range-of-motion exercises. All this exercise keeps the joints active and protects against them freezing up.

The third treatment is to control the pain. Losing mobility in your joints due to arthritis can be very frustrating, but the pain that accompanies it can be downright agonizing. Sometimes a simple anti-inflammatory will do the trick, but for bigger arthritis pain you need something powerful. That's why many doctors turn to Tramadol to help their patients cope with the intense pain associated with arthritis.

While there is no cure for arthritis, the combination of these factors allows people with arthritis to live a relatively normal life, taking part in activities they've enjoyed all their lives.

Source: http://www.articlesnatch.com

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Tramadol (ultram) and Gelonida - Potent Painkillers

Author: Vlad Kott

Copyright (c) 2008 Vlad Kott

Tramadol (Ultram) is prescribed to relieve moderate to moderately severe pain, to treat pain caused by surgery and chronic conditions such as cancer or joint pain. It works by decreasing the body's sense of pain.

Gelonida is a narcotic analgesic used to treat or prevent moderate to severe pain.

* Most important fact about Tramadol (Ultram)

You should not drive a car, operate machinery, or perform any other potentially hazardous activities until you know how Tramadol Ultram affects you.

It's important to take Tramadol exactly as prescribed. Do not increase the dosage or length of time you take Ultram without your doctor's approval.

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Ultram.

Side effects may include:

Agitation, anxiety, bloating and gas, constipation, convulsive movements, diarrhea, dizziness, drowsiness, dry mouth, feeling of elation, hallucinations, headache, indigestion, itching, nausea, nervousness, sweating, tremor, vomiting, weakness.

Avoid Tramadol Ultram if it has ever given you an allergic reaction. Also avoid Tramadol Ultram after taking large doses of sleeping pills such as Halcion, Dalmane, and Restoril; narcotic pain relievers such as Demerol, morphine, Darvon, and Percocet; or psychotherapeutic drugs such as antidepressants and tranquilizers. And do not take Tramadol Ultram after drinking excessive amounts of alcohol.

If you have stomach problems such as an ulcer, make sure your doctor is aware of them. Tramadol Ultram may hide the symptoms, making them difficult to diagnose and treat.

Tramadol Ultram can cause mental and physical addiction. If you've ever had a problem with narcotic painkillers such as Percocet, Demerol, or morphine, you should avoid Tramadol Ultram. Withdrawal symptoms may occur if you stop taking Tramadol Ultram abruptly. Such symptoms include anxiety, sweating, insomnia, pain, nausea, tremor, diarrhea, and respiratory problems. A gradual decrease in dosage will help prevent these symptoms.

Do not take more than the recommended dose of Tramadol Ultram, since larger doses have been known to cause seizures, especially if you have epilepsy or are taking medications that also increase the risk of seizures. Among such medications are almost all antidepressant drugs, plus narcotics and major tranquilizers such as Loxitane and Stelazine.

If you have liver or kidney disease, be sure your doctor knows about it. Your dosage may have to be reduced.

Before you have any kind of surgery, make sure the doctor knows you are taking Tramadol Ultram.

If you have any kind of breathing problem, use Tramadol Ultram with caution or take a different kind of painkiller. Tramadol Ultram can impair respiration, especially if taken with alcohol.

If you have experienced a head injury, consult your doctor before taking Tramadol Ultram. The medication's effects may be stronger and could hide warning signs of serious trouble.

Tramadol Ultram may increase the drowsiness caused by alcohol. Do not drink alcohol while taking Tramadol Ultram.

There have been reports of serious harm to developing babies when Tramadol Ultram was used during pregnancy. If you are pregnant or plan to become pregnant, tell your doctor immediately.

Tramadol Ultram appears in breast milk and may affect a nursing infant. If Tramadol Ultram is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Avoid Tramadol Ultram, too, if you are taking the seizure medication Tegretol.

Symptoms of Ultram overdose include:

Difficult or slowed breathing, drowsiness, coma, seizures, cardiac arrest. Tramadol can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.

***** Gelonida *****

Gelonida - generic name is parecoxib sodium. It is used to treat or prevent moderate to severe pain.

* Side effects

That may go away during treatment, include drowsiness, dizziness, constipation, or nausea. If they continue or are bothersome, check with your doctor.

Check with your doctor if you experience vomiting, skin rash, itching, slowed or difficult breathing, difficulty urinating, or fainting.

Don't take this drug if you are also taking Quinidine. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding.

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include cold and clammy skin, slowed breathing, slowed heartbeat, drowsiness, dizziness, lightheadedness, deep sleep, and loss of consciousness.

Avoid alcohol while you are using this drug. This drug will add to the effects of alcohol and other depressants.

Don't drive, don't operate machinery until you know how you react to this medicine? Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.

Don't take this drug if you have had a severe allrgic reaction to Codeine, Hydrocodone, Dihydrocodeine, or Oxycodone (such as Tylox, Tylenol with Codeine, Vicodin).

A severe allergic reaction includes a severe rash, hives, breathing difficulties, or dizziness.
Source: http://www.articlesbase.com

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